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Study identifier: NCT03633110 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccine

Condition: Cutaneous Melanoma · Non-small Cell Lung Cancer · Squamous Cell Carcinoma of the Head and Neck  ·  Sponsor: Genocea Biosciences, Inc.

PhasePhase 1/Phase 2
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

In this study, Genocea is evaluating an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors. A proprietary tool developed by Genocea, called ATLAS™ (Antigen Lead Acquisition System) will be used to identify neoantigens in each patient's tumor that are recognized by their CD4 and/or CD8 T cells. ATLAS-identified neoantigens will then be incorporated into a patient's personalized vaccine in the form of synthetic long peptides (SLPs).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (11)

UC San Diego Moores Cancer CenterLa Jolla, California, United States
John Wayne Cancer Institute - Providence Saint John's Health CenterSanta Monica, California, United States
University of Colorado, Anschutz Cancer PavilionAurora, Colorado, United States
Dana-Farber Cancer InstituteBoston, Massachusetts, United States
Karmanos Cancer InstituteDetroit, Michigan, United States
University of Nebraska Medical CenterOmaha, Nebraska, United States
Columbia University Medical Center - Herbert Irving PavilionNew York, New York, United States
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United States
The Sarah Cannon Research InstituteNashville, Tennessee, United States
The University of Texas MD Anderson Cancer CenterHouston, Texas, United States
University of Wisconsin Carbone Cancer CenterMadison, Wisconsin, United States

Sponsor or site team? See the site landscape for this trial — listed sites, countries, and recruiting-density context.

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