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Condition: Avutometinib Synced from ClinicalTrials.gov · August 05, 2026

Recruiting studies: Avutometinib

Studies currently listed as recruiting on the public registry for this search term. Each page explains the study in plain language, with locations and the study team's contact details. Clinicians: generate a printable list for your patient →

Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung
Phase 2 · 3 location(s) · Emory University · NCT06495125
A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
Phase 2 · 8 location(s) · Memorial Sloan Kettering Cancer Center · NCT06394804
Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutan
Phase 1/Phase 2 · 2 location(s) · University of Utah · NCT06194929
A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT05787561
A Study of Avutometinib and Defactinib in People With Thyroid Cancer
Phase 2 · 7 location(s) · Memorial Sloan Kettering Cancer Center · NCT06007924
VS-6766+Abema+Fulv in Met HR+/HER- BC
Phase 1/Phase 2 · 3 location(s) · Adrienne G. Waks · NCT05608252
Avutometinib and Defactinib in Diffuse Gastric Cancer
Phase 2 · 1 location(s) · Ryan H. Moy, MD, PhD · NCT06487221
Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in
Phase 2 · 1 location(s) · M.D. Anderson Cancer Center · NCT06369259
5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours
Phase 1/Phase 2 · 3 location(s) · Institute of Cancer Research, United Kingdom · NCT06630260
A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib
Phase 2 · 4 location(s) · University of Oklahoma · NCT05512208
Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer
Phase 1 · 1 location(s) · M.D. Anderson Cancer Center · NCT07318324
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
Phase 3 · 106 location(s) · Verastem, Inc. · NCT06072781
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