Condition: DLBCL - Diffuse Large B Cell Lymphoma · Pirtobrutinib · Sponsor: Changzhou No.2 People's Hospital
This is a single-arm, open-label, multicenter clinical study evaluating the efficacy and safety of pirtobrutinib combined with Pola-R-CHP in previously untreated Non-GCB DLBCL. PET/CT assessment will be performed after 3 cycles of combination therapy. Patients achieving CR/PR will continue treatment for another 3 cycles, while those with PD/SD will be discontinued from the study. Patients achieving CR/PR after 6 cycles of treatment will undergo follow-up with PET/CT or contrast-enhanced CT every 3 months during the first year and every 6 months thereafter, until disease progression, death, withdrawal of informed consent, or study completion, whichever occurs first.
This description comes directly from the study's public registry record.
Jianyong Li, PhD · lijianyonglm@126.com
Always discuss trial participation with your own doctor first.
| Jiangsu Province Hospital The First Affiliated Hospital with Nanjing Medical University | Nanjing, Jiangsu, China | — |
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