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Study identifier: NCT07730450 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age

Condition: COVID-19 Vaccines  ·  Sponsor: BioNTech SE

PhasePhase 4
Planned participants200
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersYes

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The purpose of this study is to learn about the safety and effects of an updated COVID-19 vaccine (called BNT162b2) in adults 18 to 64 years of age. This study is seeking participants who: * are medically stable * have not had a recent COVID-19 infection * have not had a recent vaccination * do not have medical conditions that increase their risk of complications from COVID-19 All participants in this study will randomly receive 1 injection into their arm of either: * BNT162b2 vaccine which targets COVID-19 and is selected for the 2026-2027 COVID-19 season, or * Tdap vaccine which targets tetanus, diphtheria, and pertussis (whooping cough). The study team and participants will not know which injection they receive. We will evaluate safety and SARS-CoV-2 spike protein levels in people receiving each of these vaccines. Participants will be in the study for about 12 months.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (5)

Diablo Clinical Research, LLC dba Flourish ResearchWalnut Creek, California, United StatesRecruiting
Palm Springs Community Health CenterMiami Lakes, Florida, United StatesRecruiting
East-West Medical Research InstituteHonolulu, Hawaii, United StatesRecruiting
Duke Vaccine and Trials UnitDurham, North Carolina, United StatesRecruiting
J. Lewis Research, Inc. / Foothill Family ClinicSalt Lake City, Utah, United StatesRecruiting

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