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Study identifier: NCT07683000 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Study of Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults With HIV-1 on Stable Oral Treatment Regimens

Condition: HIV-1-infection  ·  Sponsor: Gilead Sciences

PhasePhase 3
Planned participants590
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical study is to compare how effective a long-acting treatment of injectable combination of lenacapavir (LEN), teropavimab (TAB), and zinlirvimab (ZAB) is versus continuing a daily oral HIV treatment in adults with HIV-1 whose virus is already well controlled, after 1 year (52 weeks) of treatment. The primary objective of this study is to evaluate the efficacy of switching to the regimen of LEN, TAB, and ZAB versus continuing an oral stable baseline regimen (SBR) in virologically suppressed people with HIV-1 (PWH) as determined by the proportion of participants with HIV-1 RNA ≥ 50 copies/mL at Week 52.

This description comes directly from the study's public registry record.

Talk to the study team

Gilead Clinical Study Information Center  ·  1-833-445-3230 (GILEAD-0)  ·  GileadClinicalTrials@gilead.com

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Locations (2)

Be Well Medical CenterBerkeley, Michigan, United StatesRecruiting
Clinical Alliance for Research & Education - Infectious Diseases, LLC (CARE-ID)Annandale, Virginia, United StatesRecruiting

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