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Study identifier: NCT07680946 Synced from ClinicalTrials.gov · August 10, 2026
● Study status: Recruiting

Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophrenia

Condition: Schizophrenia  ·  Sponsor: TG Therapeutics, Inc.

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where2 locations

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.Open the site landscape →

About this study

The main objective of this Phase 2 study is to assess the efficacy of ublituximab as measured by positive and negative syndrome scale (PANSS) total score in participants with schizophrenia.

This description comes directly from the study's public registry record.

Talk to the study team

TG Therapeutics Clinical Support Team  ·  1-877-575-8489  ·  clinicalsupport@tgtxinc.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: 1. Primary diagnosis of schizophrenia. 2. Treatment-resistant. 3. Requires antipsychotic treatment and is currently receiving "standard of care". 4. PANSS total score between 80 and 120, inclusive at screening and baseline. Exclusion Criteria 1. Any primary Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) disorder other than schizophrenia. 2. Ongoing clozapine treatment. 3. Risk for suicidal behavior. 4. Any severe or uncontrolled medical condition that could affect the participant's ability to participate. Note: Other protocol-specified Inclusion/Exclusion criteria may apply

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (2)

TG Therapeutics Investigational Trial SiteLittle Rock, Arkansas, United StatesRecruiting
TG Therapeutics Investigational Trial SiteRichardson, Texas, United StatesRecruiting

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

Little RockRichardson

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