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Study identifier: NCT07654972 Synced from ClinicalTrials.gov · August 10, 2026
● Study status: Recruiting

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

Condition: Obesity · Overweight  ·  Sponsor: Eli Lilly and Company

PhasePhase 1
Planned participants108
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYesCheck eligibility criteria ↓
Where3 locations · 2 countries

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

The main purpose of this study is to understand how safe and well-tolerated LY4174794 is in participants with obesity or overweight who are otherwise healthy. Blood tests will be performed to check how much LY4174794 gets into the bloodstream and how long it takes the body to eliminate it. Participation in this study will last about 35 to 45 weeks (7 to 11 months).

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Are overtly healthy with no comorbidities related to body mass index (BMI), such as type 2 diabetes mellitus or unstable cardiovascular disease * Are overweight with a BMI of ≥27 kilogram per meter square (kg/m²), or have obesity with a BMI of ≥30 kg/ m² * Have had a self-reported stable weight for 3 months prior to screening Exclusion Criteria: * Have a history or presence of cardiovascular, respiratory, hepatic, renal, GI, endocrine, hematological, or neurological disorders capable of significantly altering the absorption, metabolism, or elimination of drugs, or of constituting a risk when taking the study intervention, or of interfering with the interpretation of data * Is an individual of childbearing potential (IOCBP)

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (3)

ICON Early Phase Services, LLCSan Antonio, Texas, United StatesRecruiting
ICON Early Phase Services, LLCSalt Lake City, Utah, United StatesNot Yet Recruiting
Lilly Centre for Clinical PharmacologySingapore, SingaporeNot Yet Recruiting

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

San AntonioSalt Lake CitySingapore

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