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Study identifier: NCT07571005 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

Condition: Obesity · Overweight · Obstructive Sleep Apnoea  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with excess body weight and obstructive sleep apnoea not treated with positive airway pressure lose weight and improve sleep apnoea. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it) and which treatment participants get is decided by chance.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (80)

Artemis Insitute for Clin ResSan Diego, California, United StatesRecruiting
PharmaDev Clinical Research Institute LLCMiami, Florida, United StatesRecruiting
Essence MD ResearchNaples, Florida, United StatesNot Yet Recruiting
Renstar Medical ResearchOcala, Florida, United StatesRecruiting
Conquest ResearchAtlanta, Georgia, United StatesRecruiting
Physicians Research AssociatesLawrenceville, Georgia, United StatesRecruiting
University Of ChicagoChicago, Illinois, United StatesRecruiting
Weil Cornell MedicineNew York, New York, United StatesRecruiting
CTI Clinical Research CenterCincinnati, Ohio, United StatesRecruiting
Clinical Research Associates of Central PA, LLCDuBois, Pennsylvania, United StatesNot Yet Recruiting
Epic Medical ResearchDeSoto, Texas, United StatesRecruiting
Advanced Neurology Epilepsy and Sleep Center ANESCEl Paso, Texas, United StatesRecruiting

+ 68 more locations — full list on the registry record.

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