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Study identifier: NCT07530198 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

HIV Therapeutic DNA Vaccine (ICVAX) Phase I Clinical Trial in Hong Kong

Condition: Human Immunodeficiency Virus · Human Immunodeficiency Virus I Infection  ·  Sponsor: Immuno Cure Holding (HK) Limited

PhasePhase 1
Planned participants22
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this randomized clinical trial is to evaluate the safety and immunogenicity of the HIV Therapeutic DNA Vaccine (ICVAX) in participants with HIV-1 infection under antiretroviral therapy (ART). The study compares three delivery methods - Teresa -EPT I, PharmaJet Tropis, and PapiVax TriGrid EP - to induce antigen-specific T cell responses in the participants. The primary objectives are to evaluate the safety of ICVAX delivered using three different devices in the participants within the period Day 0-Day 336, and to evaluate the antigen-specific T cell responses induced by ICVAX in the participants within the period Day 0-Day 168. The participants will receive four injections of ICVAX administered at 4-week intervals. Following the final dose, participants will be monitored for 36 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Grace Chung Yan Lui, Dr.  ·  (852) 5569 9539  ·  gracelui@cuhk.edu.hk

Always discuss trial participation with your own doctor first.

Locations (1)

The Chinese University of Hong Kong Phase 1 Clinical Trial Centre at Prince of Wales HospitalShatin, New Territories, Hong KongRecruiting

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