Condition: Inflammation · Inflammation Biomarkers · Blood Sampling · Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
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The purpose of this study is to see whether dried blood spot (DBS) samples can measure inflammatory biomarkers as accurately as venous blood samples. Investigators will be measuring inflammatory biomarkers changes obtained in DBS compared with paired venous blood samples following a controlled physiological stressor (i.e. after a vaccine or other planned event that can cause a temporary rise in inflammation). These findings will help understand whether DBS can be a reliable alternative to traditional blood draws in future research and healthcare.
This description comes directly from the study's public registry record.
Kristen Moran, BSc. · 514-934-1934 · cpau.med@mcgill.ca
Evelyn Laferrière, BSc. · 514-934-1934 · cpau.med@mcgill.ca
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Men or women aged ≥18 years, who are planning to receive a seasonal vaccine OR have a scheduled acute stressor\*. Exclusion Criteria: * Any infectious symptoms (fever, cough, rhinorrhea, sore throat, diarrhea, loss of smell or taste) within the previous 7 days * Any self-reported active/recent use of cocaine, injection drugs, or amphetamines * Acute worsening of a known chronic health condition within the previous 30 days (e.g., of IBD, COPD, asthma, rheumatologic disease) * Known severe allergy or intolerance to the planned vaccine * Contraindication to the vaccine received, if applicable \*List of possible scheduled acute stressors include: * Hard exercise (incl. 10km run or longer, high-intensity interval training, or comparable endurance activity) * Social event with moderate alcohol consumption * Planned change in medication dose and/or frequency of use * Onset of menstruation (day 1) * Other pre-planned stressors expected to elicit an inflammatory response
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Research Institute of the McGill University Health Centre | Montreal, Quebec, Canada | Recruiting |
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