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Study identifier: NCT07434518 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

A Real-World Study Evaluating the Efficacy and Safety of Adebrelimab in Patients With Advanced SCLC

Condition: Small Cell Lung Cancer (SCLC)  ·  Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The goal of this observational study is to evaluate the safety and efficacy of adebrelimab in the perioperative and advanced-stage treatment of small cell lung cancer (SCLC) under real-world conditions. The main questions it aims to answer are: 1. The safety of adebrelimab treatment in patients with advanced SCLC under real-world conditions, with a specific focus on the incidence of grade ≥3 immune-related adverse events. Safety monitoring begins when patients start receiving adebrelimab treatment and continues until 90 days after the last dose of adebrelimab. 2. Observe and evaluate the efficacy of adebrelimab in patients with small cell lung cancer under real-world conditions. This includes overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and disease control rate (DCR). Additionally, the study seeks to further explore the impact of patient baseline characteristics, such as brain metastases or liver metastases, and biomarkers on prognosis.

This description comes directly from the study's public registry record.

Talk to the study team

Qingnan Zhao, PhD  ·  +86 (021)37798597  ·  zhaoqingnan2010@126.com

Qian Xue, PhD  ·  +86 (021)37798597

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai General HospitalShanghai, ChinaRecruiting

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