Condition: Diabetes Mellitus, Type 2 · Sponsor: Novo Nordisk A/S
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This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to placebo or semaglutide. The purpose of this clinical study is to find out if NNC0662-0419 is effective and safe for treating people living with type 2 diabetes. Participants will get either NNC0662-0419, semaglutide or placebo. Which treatment participants get is decided by chance. NNC0662-0419 is a new medicine which cannot be prescribed by doctors but has previously been tested in humans. Semaglutide is an approved medication to treat type 2 diabetes.
This description comes directly from the study's public registry record.
Novo Nordisk · (+1) 866-867-7178 · clinicaltrials@novonordisk.com
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion criteria * Male or female (sex at birth). * Age 18-75 years (both inclusive) at the time of signing the informed consent. * Glycated haemoglobin (HbA1c) of 7.0-10.0 percent (%) (53-86 millimoles per mole \[mmol/mol\]) (both inclusive) as assessed by central laboratory at screening. * Willingness to obtain a high weight loss (greater than \[\>\] 25% of weight at baseline). Exclusion criteria * Treatment with any medication for the indication of diabetes or obesity other than stated in the inclusion criteria within 90 days before screening. However, short term insulin treatment for a maximum of 14 consecutive days and prior insulin treatment for gestational diabetes are allowed. * Uncontrolled and potentially unstable diabetic retinopathy or maculopathy. Pharmacological pupil-dilation is a requirement unless using a digital fundus photography camera specified for non-dilated examination. * Known hypoglycaemic unawareness as indicated by the investigator according to Clarke's Questionnaire.
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| First Valley Medical Group | Lancaster, California, United States | Recruiting |
| Torrance Clinical Research Institute, Inc. | Lomita, California, United States | Recruiting |
| Ark Clinical Research | Long Beach, California, United States | Recruiting |
| Pacific Clinical Studies | Los Alamitos, California, United States | Recruiting |
| Wetlin Research Associates, Inc. | San Diego, California, United States | Recruiting |
| Diablo Clinical Research, Inc. | Walnut Creek, California, United States | Recruiting |
| Encore Medical Research LLC | Hollywood, Florida, United States | Recruiting |
| Bioclinical Research Alliance | Miami, Florida, United States | Recruiting |
| South Broward Research LLC | Miramar, Florida, United States | Recruiting |
| West Orange Endocrinology | Ocoee, Florida, United States | Not Yet Recruiting |
| Encore Medical Research of Weston | Weston, Florida, United States | Recruiting |
| Elite Clinical Trials | Blackfoot, Idaho, United States | Recruiting |
+ 51 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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