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Study identifier: NCT07415954 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2  ·  Sponsor: Novo Nordisk A/S

PhasePhase 2
Planned participants270
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where63 locations · 10 countries

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to placebo or semaglutide. The purpose of this clinical study is to find out if NNC0662-0419 is effective and safe for treating people living with type 2 diabetes. Participants will get either NNC0662-0419, semaglutide or placebo. Which treatment participants get is decided by chance. NNC0662-0419 is a new medicine which cannot be prescribed by doctors but has previously been tested in humans. Semaglutide is an approved medication to treat type 2 diabetes.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion criteria * Male or female (sex at birth). * Age 18-75 years (both inclusive) at the time of signing the informed consent. * Glycated haemoglobin (HbA1c) of 7.0-10.0 percent (%) (53-86 millimoles per mole \[mmol/mol\]) (both inclusive) as assessed by central laboratory at screening. * Willingness to obtain a high weight loss (greater than \[\>\] 25% of weight at baseline). Exclusion criteria * Treatment with any medication for the indication of diabetes or obesity other than stated in the inclusion criteria within 90 days before screening. However, short term insulin treatment for a maximum of 14 consecutive days and prior insulin treatment for gestational diabetes are allowed. * Uncontrolled and potentially unstable diabetic retinopathy or maculopathy. Pharmacological pupil-dilation is a requirement unless using a digital fundus photography camera specified for non-dilated examination. * Known hypoglycaemic unawareness as indicated by the investigator according to Clarke's Questionnaire.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (63)

First Valley Medical GroupLancaster, California, United StatesRecruiting
Torrance Clinical Research Institute, Inc.Lomita, California, United StatesRecruiting
Ark Clinical ResearchLong Beach, California, United StatesRecruiting
Pacific Clinical StudiesLos Alamitos, California, United StatesRecruiting
Wetlin Research Associates, Inc.San Diego, California, United StatesRecruiting
Diablo Clinical Research, Inc.Walnut Creek, California, United StatesRecruiting
Encore Medical Research LLCHollywood, Florida, United StatesRecruiting
Bioclinical Research AllianceMiami, Florida, United StatesRecruiting
South Broward Research LLCMiramar, Florida, United StatesRecruiting
West Orange EndocrinologyOcoee, Florida, United StatesNot Yet Recruiting
Encore Medical Research of WestonWeston, Florida, United StatesRecruiting
Elite Clinical TrialsBlackfoot, Idaho, United StatesRecruiting

+ 51 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

LancasterLomitaLong BeachLos Alamitos

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