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Study identifier: NCT07342114 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

A Dose-Escalation Study of RO7875913 in Healthy Participants

Condition: Healthy Volunteers  ·  Sponsor: Genentech, Inc.

PhasePhase 1
Planned participants40
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYesCheck eligibility criteria ↓
WhereChristchurch, Canterbury, New Zealand

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of RO7875913 in healthy participants.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GO46451 https://forpatients.roche.com/ No email attachments.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Agreement to adhere to the contraception requirements * Body weight \> 40 kilogram (kg) with a body mass index of 18-30 kg per meter square (kg/m\^2) Exclusion Criteria: * Positive test result for hepatitis B surface antigen, hepatitis C virus (HCV), or human immunodeficiency virus (HIV) antibody screen * History of any malignancy * Major surgical procedure within 28 days prior to initiation of study treatment, or anticipation of need for a major surgical procedure during the study * History or clinical manifestations of significant metabolic, hepatic, renal, pulmonary, cardiovascular, hematologic, gastrointestinal, urologic, neurologic, or psychiatric disorders * Known allergy or hypersensitivity to any component of the RO7875913 formulation * Treatment with investigational biologic therapy (or blinded comparator) within 90 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug * Treatment with investigational non-biologic therapy (or blinded comparator) within 28 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug * Treatment with any immunosuppressive medication within 28 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

New Zealand Clinical Research - ChristchurchChristchurch, Canterbury, New ZealandRecruiting

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