EICHORCondition: Chronic Hepatitis D Infection · Sponsor: Mirum Pharmaceuticals, Inc.
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
This is a Phase 3, global, randomized, open-label, multicenter trial designed to evaluate the safety and efficacy of chronic treatment with brelovitug (BJT-778) for chronic hepatitis delta virus (HDV) infection. The objective of this study is to test the safety and effectiveness of brelovitug compared to delayed treatment.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: 1. Willing and able to provide written informed consent 2. Chronic HDV infection 3. HDV RNA \>500 IU/mL at Screening 4. ALT \>ULN at Screening 5. Willing to take or already taking HBV nucleos(t)ide therapy. Exclusion Criteria: 1. Pregnant or nursing females 2. Unwilling to comply with contraception requirements during the study 3. Difficulty with blood collection and/or poor venous access for the purposes of phlebotomy 4. Clinical hepatic decompensation (i.e., ascites, encephalopathy variceal hemorrhage). 5. Solid organ or bone marrow transplantation 6. Presence of other liver disease(s) (non-HBV/HDV), such as metabolic dysfunction-associated steatohepatitis (MASH), alcohol associated hepatitis, cholestatic liver disease, hepatocellular carcinoma. Note - Other protocol-defined Inclusion/Exclusion criteria apply.
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| University of California, Davis | Davis, California, United States | — |
| Kaiser Permanente Medical Center | Sacramento, California, United States | — |
| Quest Clinical Research | San Francisco, California, United States | — |
| Denver Health Medical Center | Denver, Colorado, United States | — |
| Alliance Clinical, Las Vegas | Las Vegas, Nevada, United States | — |
| Cleveland Clinic | Cleveland, Ohio, United States | — |
| Prime Clinical Research Inc | Mansfield, Texas, United States | — |
| University of Utah | Salt Lake City, Utah, United States | — |
| Erasme Hospital | Brussels, Belgium | — |
| University Hospital Antwerp (UZA) | Edegem, Belgium | — |
| University Hospital Center Sart-Tilman | Liège, Belgium | — |
| Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda | Sofia, Bulgaria | — |
+ 15 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07298330