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Study identifier: NCT07288177 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer (NSCLC)  ·  Sponsor: Genmab

PhasePhase 2
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 2 study will be conducted in different countries around the world with up to about 240 participants. The purpose of this study is to evaluate how well Rina-S works against lung cancer. The treatment in this study is Rina-S monotherapy (by itself). All participants will receive active drug; no one will be given placebo. The treatment duration will be different for every participant, but an average of 12 months is expected. Participants will be asked to attend 1 to 5 visits at the study clinic for each cycle (duration of cycle is 3 weeks). If a participant's cancer stays the same or gets better, and there are not any serious problems, participants can keep getting study treatment for as long as the study is open. Participation in the study will require visits to the study site(s). During site visits, there will be various tests (such as blood draws) and procedures (such as recording of heart activity, imaging/X-rays) to monitor whether the study treatment is safe and effective.

This description comes directly from the study's public registry record.

Talk to the study team

Genmab Trial Information  ·  +4570202728  ·  clinicaltrials@genmab.com

Always discuss trial participation with your own doctor first.

Locations (57)

Compassionate Cancer Care CenterFountain Valley, California, United StatesRecruiting
Providence Medical Foundation (St. Joseph Heritage Healthcare)Santa Rosa, California, United StatesRecruiting
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United StatesRecruiting
Moffitt Cancer Center and Research InstituteTampa, Florida, United StatesRecruiting
Emory Winship Cancer InstituteAtlanta, Georgia, United StatesRecruiting
St. Vincent Frontier Cancer CenterBillings, Montana, United StatesRecruiting
Nebraska Hematology-OncologyLincoln, Nebraska, United StatesRecruiting
Astera Cancer CareEast Brunswick, New Jersey, United StatesRecruiting
ONE Onc: New York Oncology HematologyAlbany, New York, United StatesRecruiting
Montefiore Medical ParkThe Bronx, New York, United StatesRecruiting
UNC Health - University of North CarolinaChapel Hill, North Carolina, United StatesRecruiting
Providence Portland Medical CenterPortland, Oregon, United StatesRecruiting

+ 45 more locations — full list on the registry record.

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