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Study identifier: NCT07282340 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Recruiting

Phentermine's Impact on Treatment in Teens

Condition: Childhood Obesity  ·  Sponsor: Russell McCulloh, MD

PhasePhase 2
Planned participants240
Who can joinAll sexes, 12 Years to 17 Years
Healthy volunteersNo

About this study

PhITT is a Phase IIb, multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of phentermine (16 mg daily) in adolescents aged 12 to \<18 years with obesity. Conducted across approximately 10 sites within the IDeA States Pediatric Clinical Trials Network (ISPCTN), the study aims to enroll up to 240 participants and then randomize up to 198 who meet eligibility criteria, randomized in a 2:1 ratio to phentermine or placebo over a 52-week treatment period, followed by a 2-week withdrawal assessment.

This description comes directly from the study's public registry record.

Talk to the study team

Aubrey VanStory  ·  402-559-4815  ·  aubrey.vanstory@unmc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of New Mexico Health Sciences CenterAlbuquerque, New Mexico, United StatesRecruiting
Prisma Health-Midlands Children's HospitalColumbia, South Carolina, United StatesRecruiting

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