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Study identifier: NCT07277660 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

Condition: Atopic Dermatitis  ·  Sponsor: UCB Biopharma SRL

PhasePhase 2
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where68 locations · 9 countries

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The purpose of the study is to evaluate the dose-response relationship of galvokimig compared with placebo in study participants with moderate-to-severe atopic dermatitis (AtD).

This description comes directly from the study's public registry record.

Talk to the study team

UCB Cares  ·  +18445992273  ·  ucbcares@ucb.com

UCB Cares  ·  0018445992273  ·  UCBCares@ucb.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Participant must be aged greater than or equal (≥)18 years at the time of signing the informed consent * Participant has chronic atopic dermatitis (AtD) (according to American Academy of Dermatology Consensus Criteria) that has been present for at least ≥1 year prior to initiating the study (ie, signing of the informed consent form \[ICF\]) and with: 1. validated Investigator Global Assessment (vIGA) score ≥3 at Screening and Baseline 2. Eczema Area and Severity Index (EASI) score ≥16 at both Screening and Baseline 3. Peak Pruritus Numerical Rating Scale (PP-NRS) score of ≥4 at both Screening and Baseline 4. ≥10% body surface area (BSA) of AtD involvement at both Screening and Baseline 5. Documented recent history (within 6 months prior to Screening) of inadequate response to treatment with topical medications, or study participants for whom topical treatments are otherwise medically inadvisable (eg, due to important side effects or safety risks) and who are candidates for systemic therapy Exclusion Criteria: * Participant has any history or presence of any medical or psychiatric condition, physical examination finding, laboratory test result, or electrocardiogram (ECG) signal that, in the opinion of the investigator, could constitute a risk when taking the study intervention; or interfere with the interpretation of data and could jeopardize or would compromise the study participant's ability to participate in this study * Active dermatologic conditions that may confound the diagnosis of AtD or would interfere with assessment of treatment, such as but not limited to scabies, seborrheic dermatitis, cutaneous lymphoma, ichthyosis, psoriasis, active allergic or irritant contact dermatitis * Presence or family history (first degree) of inflammatory bowel disease (includes Crohn's disease and ulcerative colitis) * History of chronic or recurrent infections, or a serious or life-threatening infection within the 6 months prior to the Baseline (including herpes zoster) as judged by the investigator * Participants are not permitted to enroll into the study if they meet tuberculosis (TB) exclusion criteria * Previous treatment with galvokimig * Participant has relevant safety events to one or more interleukin (IL)-13 biologic response modifiers (ie, dupilumab, tralokinumab and lebrikizumab) that resulted in discontinuation and change of treatment * All systemic therapies (other than biologics), topical therapies and other treatments for AtD must be discontinued at least 4 weeks prior to Baseline * Treatment with biologic agents must discontinued at least 3 months prior to baseline

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (68)

Atd002 52021Oceanside, California, United StatesRecruiting
Atd002 52008Santa Monica, California, United StatesRecruiting
Atd002 52013Boca Raton, Florida, United StatesRecruiting
Atd002 52007Miami, Florida, United StatesRecruiting
Atd002 52003Miami, Florida, United StatesRecruiting
Atd002 52015Savannah, Georgia, United StatesRecruiting
Atd002 52017Chicago, Illinois, United StatesRecruiting
Atd002 52018Wheaton, Illinois, United StatesRecruiting
Atd002 52012New Albany, Indiana, United StatesRecruiting
Atd002 52014Bowling Green, Kentucky, United StatesRecruiting
Atd002 52001Troy, Michigan, United StatesRecruiting
Atd002 52009Troy, Michigan, United StatesRecruiting

+ 56 more locations — full list on the registry record.

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