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Study identifier: NCT07265596 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

Condition: Prodromal Parkinsons Disease  ·  Sponsor: Michael J. Fox Foundation for Parkinson's Research

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The study is a longitudinal, multi-center study to assess progression of \[18F\] AV-133 imaging in Prodromal PD participants. Participants will be followed for up to 24 months. Approximately 100 Prodromal participants will be recruited from up to 10 sites. Participants will be comprehensively assessed at baseline and follow up. Participants will undergo imaging assessments with \[18F\] AV-133 and clinical (motor, neuropsychiatric, cognitive and imaging and biomarker) assessments (conducted under the PPMI Clinical protocol).

This description comes directly from the study's public registry record.

Talk to the study team

Lianne Ramia  ·  203-590-5600  ·  LRamia1@indd.org

Jessica Dimos  ·  203-590-5600  ·  jdimos@indd.org

Always discuss trial participation with your own doctor first.

Locations (8)

Institute for Neurodegenerative DisordersNew Haven, Connecticut, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Toronto Western HospitalToronto, Ontario, CanadaNot Yet Recruiting
Philipps-University of MarburgHessen, GermanyNot Yet Recruiting
Tel Aviv Sourasky Medical CenterTel Aviv, IsraelNot Yet Recruiting
Radboud UniversityNijmegen, Gelderland, NetherlandsNot Yet Recruiting
Queen Mary University of LondonLondon, Britain, United KingdomRecruiting
Newcastle UniversityNewcastle upon Tyne, Tyne and Wear, United KingdomRecruiting

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