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Study identifier: NCT07262164 Synced from ClinicalTrials.gov · August 09, 2026
● Study status: Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2062 in Patients With Solid Tumors

Condition: Advanced Malignant Solid Tumor  ·  Sponsor: Shanghai Virogin Biotech Co., Ltd.

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNoCheck eligibility criteria ↓
WhereHebei, China

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

VG2062 is a Recombinant Human IL12/15 Dual-Regulated Oncolytic HSV-1 Injection. This Phase I study will be conducted in herpes simplex virus (HSV) -seropositive subjects with advanced malignant solid tumors that are refractory to conventional therapies. This is an open label study to determine the safety and tolerability of VG2062, and recommended dose of VG2062 for Phase II trials.

This description comes directly from the study's public registry record.

Talk to the study team

Shu hang Wang  ·  13581809307  ·  wangshuhang@cicams.ac.cn

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: 1. Signed written informed consent form. 2. Age 18 to 75 years (inclusive), male or female. 3. Subject with advanced malignant solid tumors who have failed standard treatment and for whom there is no effective treatment at this stage. 4. Eligible patients of childbearing potential (male and female) must agree to use a reliable method of contraception during the trial and for at least 90 days after dosing; females of childbearing potential must have a negative blood pregnancy test 7 days before enrollment. Exclusion Criteria: 1. Subjects who have received other unlisted drugs clinical trial treatment 4 weeks before the first dose of the study drug. 2. Subjects who underwent major organ surgery (excluding needle biopsy) or had significant trauma 4 weeks before the first dose of the study drug. 3. In the herpes simplex virus recurrence and infection period, and there are corresponding clinical manifestations, such as oral herpes labialis, herpetic keratitis, herpetic dermatitis, genital herpes and so on. 4. Other active uncontrolled infection. 5. Known alcohol or drug dependence. 6. Subjects with mental disorders or poor compliance. 7. Women who are pregnant or breastfeeding. 8. Subjects in the opinion of the investigator are not suitable for this clinical study due to other serious systemic diseases or other reasons.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

No. 67, Huayuan Road, Langfang Economic and Technological Development Zone, Hebei ProvinceHebei, ChinaRecruiting

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Hebei

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