EICHORCondition: Heart Failure · Sponsor: Netherlands Heart Institute
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The goal of this clinical trial is to learn whether taking selenium and coenzyme Q10 (CoQ10) can reduce HF related events and deaths related to cardiovascular disease. Researchers will compare selenium-CoQ10 supplements with a placebo to see if the supplements improve heart health and patient outcomes. Participants will: Receive either selenium-CoQ10 or placebo in addition to their usual heart failure treatment Attend standard clinical visits according to routine clinical care. The study will include 1,100 adults with chronic heart failure. Selenium and CoQ10 are natural nutrients with no known health risks. If effective, this supplement could provide a safe new way to improve outcomes for people with heart failure.
This description comes directly from the study's public registry record.
SELEQT-HF Study Team · +31 (0)503616161 · seleqt-hf@umcg.nl
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Age \>18 years * Outpatients with chronic HF, NYHA II - ambulatory IV * Serum NT-proBNP concentrations \>600 pg/mL (71 pmol/L) if in sinus rhythm; \>1000pg/mL (118 pmol/L) if in Atrial fibrillation\* Exclusion Criteria: * History of myocardial infarction, myocarditis, percutaneous intervention, cardiac surgery or stroke \<30 days * The presence of a mechanical assist device * Scheduled for mechanical assist device or heart transplant * Other non-cardiac conditions with limited life expectancy (\<1 year) * Amyloid, hypertrophic obstructive or constrictive cardiomyopathy * End stage kidney disease for which chronic intermittent peritoneal or haemodialysis * Unable to sign informed consent * (Unwilling to stop) use of over the counter supplements coQ10/selenium * Peanut and/or soy allergy
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Noordwest Ziekenhuisgroep | Alkmaar, Netherlands | Not Yet Recruiting |
| AUMC | Amsterdam, Netherlands | Not Yet Recruiting |
| Amphia Ziekenhuis | Breda, Netherlands | Recruiting |
| Catharina ziekenhuis Eindhoven | Eindhoven, Netherlands | Not Yet Recruiting |
| TREANT | Emmen, Netherlands | Not Yet Recruiting |
| University Medical Center Groningen | Groningen, Netherlands | Recruiting |
| St Antonius ziekenhuis | Nieuwegein, Netherlands | Not Yet Recruiting |
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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Source record: clinicaltrials.gov/study/NCT07234422