Condition: Major Depressive Disorder (MDD) · Sponsor: King's College London
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Depression is a prevalent and debilitating disorder. The most common treatments are antidepressant medications and talking therapies. However, for many individuals, these are not their treatment of choice. Furthermore, even following a full course of treatment with an antidepressant or talking therapy, over one third of patients continue to be unwell. The novel brain stimulation treatment, transcranial direct current stimulation (tDCS), is a potential first-line treatment for major depression. The present research question is whether home-based tDCS is an effective treatment for major depression for adults with major depression. Participants will be randomised to receive either a 10-week course of active tDCS treatment in addition to their standard care (Treatment as Usual), or to only receive Treatment as Usual. Participants will be followed up for 6-months after the start of the treatment began. After the 6-month follow-up visit, all participants from both groups can choose to continue/start the tDCS treatment. There will be a final follow-up visit 3 months later (9 months from the original treatment start of the trial).
This description comes directly from the study's public registry record.
Cynthia Fu · 020 7848 0002 · cynthia.fu@kcl.ac.uk
Always discuss trial participation with your own doctor first.
| Cardiff and Vale Health Board | Cardiff, United Kingdom | Not Yet Recruiting |
| South London and Maudsley NHS Foundation Trust | London, United Kingdom | Recruiting |
| Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust | Newcastle, United Kingdom | Not Yet Recruiting |
| Northamptonshire Healthcare NHS Foundation Trust | Northampton, United Kingdom | Not Yet Recruiting |
| Nottinghamshire Healthcare NHS Foundation Trust | Nottingham, United Kingdom | Not Yet Recruiting |
| Hampshire and Isle of Wight Healthcare NHS Foundation Trust | Southampton, United Kingdom | Not Yet Recruiting |
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