EICHORCondition: HIV -1 Infection · Sponsor: TaiMed Biologics Inc.
TMB-365 is a monoclonal antibody that binds to the CD4 receptor. TMB-380, aka VRC07-523LS is a monoclonal antibody that binds to HIV. Both interfere with HIV entry. This study is designed to test the combination of the antibodies as maintenance therapy in HIV infected suppressed individuals discontinuing oral cART for 48 weeks. Researchers will compare TMB-365/TMB-380 given IV every 8 weeks to continuation of daily oral cART to see if TMB-365/TMB-380 can also maintain viral suppression. Participants will: 1. Receive TMB-365/TMB-380 infusion or take oral cART as scheduled for 48 weeks 2. Visit the clinic as schedule for checkups and tests
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
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| Quest Clinical Research | San Francisco, California, United States | — |
| CAN Community Health Fort Lauderdale | Fort Lauderdale, Florida, United States | — |
| Midway Immunology and Research Center (MIRC) | Ft. Pierce, Florida, United States | — |
| CAN Community Health Miami Gardens | Miami Gardens, Florida, United States | — |
| Midland Medical | Oakland Park, Florida, United States | — |
| Orlando Immunology Center | Orlando, Florida, United States | — |
| CAN Community Health Sarasota | Sarasota, Florida, United States | — |
| CAN Community Health Las Vegas | Las Vegas, Nevada, United States | — |
| The Rockefeller University | New York, New York, United States | — |
| The Crofoot Research Center, Inc. | Houston, Texas, United States | — |
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Source record: clinicaltrials.gov/study/NCT07215468