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Study identifier: NCT07199959 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Study on the Mechanism of Acquired Resistance of Entrectinib

Condition: ROS1 Fusion Positive · Non Small Cell Lung Cancer  ·  Sponsor: Fudan University

PhaseN/A
Planned participants38
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

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About this study

The goal of this observational study is to learn about the mechanism of acquired resistance in first line trearment of ROS1-positive NSCLC with entrectinib. The main question it aims to answer is: what is the acquired resistant mechanism of entrectinib as first line treatment setting in patients? Tissue or blood samples of participants who have already taken entrectinib as their regular medical care for NSCLC will send for Next gene sequencing for genomic profiles and bioinformatic analysis.

This description comes directly from the study's public registry record.

Talk to the study team

Jialei Wang  ·  18017312369  ·  wangjialei@shca.org.cn

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Locations (1)

Fudan university shanghai cancer centerShanghai, Shanghai Municipality, ChinaRecruiting

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