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Study identifier: NCT07199101 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Not Yet Recruiting

Multicenter Pediatric Low-Dose CT Protocol: Development and Clinical Verification

Condition: Radiation Dose Reduction  ·  Sponsor: Beijing Children's Hospital

PhaseNA
Planned participants2650
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

Children are sensitive to ionizing radiation, and there are significant regional variations in current pediatric CT radiation doses. Although there are studies on low-dose CT targeting single lesions, these studies require clear clinical indications and support from advanced equipment, making widespread promotion difficult. The establishment of low-dose CT protocols is mostly experience-based; when radiologists lack confidence in image quality, the credibility of diagnostic reports is compromised. Therefore, the development of low-dose protocols must meet the diagnostic confidence of most radiologists, enable clear visualization of key anatomical structures in clinical practice, and satisfy the requirements for disease diagnosis. The purpose of this study is to establish a pediatric low-dose CT scanning protocol using Low-dose Simulation of CT (LDS) technology, and conduct a multicenter randomized controlled trial (RCT) in clinical settings to verify the clinical feasibility of this low-dose CT scanning protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Jihang Sun, MD  ·  +86 13521158011  ·  jihangsuns@163.com

Always discuss trial participation with your own doctor first.

Locations (20)

Beijing Children's Hospital, Capital Medical University, National Center for Children's HealthBeijing, Beijing Municipality, China
Beijing Friendship Hospital, Capital Medical UniversityBeijing, Beijing Municipality, China
Beijing Tongren Hospital, Capital Medical UniversityBeijing, Beijing Municipality, China
Medical Center for Capital Children's Health, Capital Medical UniversityBeijing, Beijing Municipality, China
National Institute for Radiological Protection, China CDCBeijing, Beijing Municipality, China
Peking Union Medical College HospitalBeijing, Beijing Municipality, China
Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders.Chongqing, Chongqing Municipality, China
Guangdong Women and Children HospitalGuangzhou, Guangdong, China
Nanfang Hospital, Southern Medical UniversityGuangzhou, Guangdong, China
Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical UniversityBaoding, Heibei, China
Fuwai Central China Cardiovascular HospitalZhengzhou, Henan, China
The Third Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, China

+ 8 more locations — full list on the registry record.

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