EICHORCondition: Healthy Adult Volunteer · Sponsor: Universiti Sains Malaysia
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Journeying along the historic Silk Road exposes travelers to dramatic dietary shifts, unfamiliar microbial environments, and the physical stresses of long-distance travel-all known to disrupt gut health and cause gastrointestinal complaints, including traveler's diarrhea and sleep disturbances. Such disruptions may also elevate the risk of acquiring antibiotic-resistant organisms. This randomized, double-blind, placebo-controlled trial evaluated whether probiotic supplementation can help maintain gut microbial balance and support traveler well-being during trips to Silk Road regions. In addition to monitoring changes in gut microbiota composition, the study assessed gastrointestinal symptoms, sleep quality, anxiety levels, overall well-being, gut immune markers, functional profiles of the microbiome, and the presence of antibiotic resistance genes.
This description comes directly from the study's public registry record.
Min Tze Liong, Ph.D. · 6046532114 · mintze.liong@usm.my
Jie Yuan, M.Sc. · 822137027899 · peanut.yuan@diprobio.com
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Generally healthy adults * Scheduled to undertake a short-term round trip (less than 7 days) to abroad * Able to complete study procedures * Willing to take intervention products Exclusion Criteria: * Use of antibiotics, probiotics, hormones, immunosuppressants, biologics or JAK inhibitors within four weeks prior to study * Chronic or severe systemic diseases (including cardiovascular, hepatic, renal, malignant or psychiatric disorders) * Uncontrolled parasitic infections * Long-term use of corticosteroids, growth hormone, vitamin B12, lysine or inositol * Major surgery within one month * Allergy to probiotic components * Other conditions deemed inappropriate by investigators
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Shanghai Jiao Tong University School of Medicine | Huangpu, Shanghai Municipality, China | Recruiting |
| Universiti Sains Malaysia | George Town, Pulau Pinang, Malaysia | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07182500