Condition: Solid Tumors · Advanced Solid Tumor · Sponsor: BeOne Medicines
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
This study is a first-in-human (FIH), Phase 1a/1b study of BG-C0902, a fully humanized anti-epidermal growth factor receptor (EGFR) and anti-mesenchymal-epithelial transition (MET) antibody, conjugated via an enzymatically cleavable linker to a topoisomerase 1 (TOPO1) inhibitor payload. The study aims to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-C0902 in participants with advanced solid tumors. The study will be conducted in 2 phases: Phase 1a (dose escalation and safety expansion) and Phase 1b (dose expansion).
This description comes directly from the study's public registry record.
Study Director · 1.877.828.5568 · clinicaltrials@beonemed.com
Always discuss trial participation with your own doctor first.
| The University of Texas Md Anderson Cancer Center | Houston, Texas, United States | Recruiting |
| Next Oncology | San Antonio, Texas, United States | Recruiting |
| Next Virginia | Fairfax, Virginia, United States | Recruiting |
| Blacktown Cancer and Haematology Centre | Blacktown, New South Wales, Australia | Recruiting |
| Cancer Research South Australia | Adelaide, South Australia, Australia | Recruiting |
| Monash Health | Clayton, Victoria, Australia | Recruiting |
| The Alfred Hospital | Melbourne, Victoria, Australia | Recruiting |
| Cancer Hospital Chinese Academy of Medical Sciences | Beijing, Beijing Municipality, China | Recruiting |
| Chongqing University Cancer Hospital | Chongqing, Chongqing Municipality, China | Recruiting |
| The First Affiliated Hospital of Xiamen University | Xiamen, Fujian, China | Recruiting |
| Henan Cancer Hospital | Zhengzhou, Henan, China | Recruiting |
| Rui Jin Hospital Shanghai Jiao Tong University School of Medicinejiading Branch | Shanghai, Shanghai Municipality, China | Recruiting |
+ 2 more locations — full list on the registry record.
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