EICHORCondition: Relapsed/Refractory B-cell Lymphoma · Sponsor: Shenzhen University General Hospital
1. Study Title: A Study on the Efficacy and Safety of Autocrine p40 CD19/CD20 Dual-Targeting Chimeric Antigen Receptor T-Cells (CD19/CD20-CAR.p40-T) in Relapsed/Refractory B-Cell Lymphoma 2. Study Objectives: * Primary Objective: To evaluate the safety of CD19/CD20 dual-targeting CAR.p40-T cell therapy in patients with relapsed/refractory B-cell lymphoma. * Secondary Objective: To evaluate the efficacy of CD19/CD20 dual-targeting CAR.p40-T cell therapy in patients with relapsed/refractory B-cell lymphoma. 3. Participant Intervention: * Participants will receive lymphodepleting chemotherapy (FC regimen: Fludarabine + Cyclophosphamide) on Days -5, -4, and -3 relative to the planned CD19/CD20-CAR.p40-T cell infusion or CD19 CAR.p40-T cell infusion. The CAR-T cell infusion will be administered 72 hours after the completion of the FC chemotherapy.
This description comes directly from the study's public registry record.
lixin wang · 0755-21839999 · wanglixin1991@sohu.com
Always discuss trial participation with your own doctor first.
| Shenzhen University General Hospital | Shenzhen, Other (Non U.s.), China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07097207