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Study identifier: NCT07074886 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

Condition: Multiple Sclerosis  ·  Sponsor: Hoffmann-La Roche

PhasePhase 2
Planned participants193
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The main purpose of this study is to assess the bioequivalence of ocrelizumab SC test formulation to the marketed ocrelizumab SC reference formulation in participants with either relapsing multiple sclerosis (RMS) or primary progressive multiple sclerosis (PPMS). The study consists of 2 phases: a controlled phase, where participants in each group will receive one dose of test or reference formulation and a continuation phase, where all participants in both groups will receive ocrelizumab SC test formulation.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (50)

Profound Research, LLCCarlsbad, California, United States
Advanced Neurology of Colorado, LLCFort Collins, Colorado, United States
Neurology Associates PAMaitland, Florida, United States
University of South FloridaTampa, Florida, United States
Johns Hopkins University School Of MedicineBaltimore, Maryland, United States
University of Massachusetts Medical SchoolWorcester, Massachusetts, United States
SUNY Upstate Medical UniversitySyracuse, New York, United States
Hope NeurologyKnoxville, Tennessee, United States
Swedish Medical CenterSeattle, Washington, United States
Centro de Especialidades Neurológicas y Rehabilitación - CENyRCABA, Buenos Aires, Argentina
Focus CECICCABA, CABA / Buenos Aires, Argentina
INECO Neurociencias OronoRosario, Santa Fe Province, Argentina

+ 38 more locations — full list on the registry record.

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