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Study identifier: NCT07071454 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Not Yet Recruiting

Preventing Early-Onset Colorectal Cancer in the VA

Condition: Colorectal Neoplasms · Mass Screening  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants536
Who can joinAll sexes, 45 Years to 49 Years
Healthy volunteersYes

About this study

Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer (EOCRC), but how to best engage younger Veterans in screening is unclear. The investigators will 1) develop and validate a novel risk score for EOCRC derived from the VA electronic health record data, 2) conduct a multilevel screening intervention that targets individuals aged 45-49 years and informs high-risk individuals and their providers about their risk status for EOCRC, and 3) determine barriers and facilitators to implementing the intervention using a qualitative process evaluation. Aim 2 is the focus of the trial. The overall goal of this study is to create and test a risk stratification approach to prevent EOCRC, which may be especially useful for younger individuals who are less likely to participate in preventive care.

This description comes directly from the study's public registry record.

Talk to the study team

Peter S Liang, MD MPH  ·  (212) 686-7500  ·  peter.liang@va.gov

Anika Zaman, MPH  ·  (212) 686-7500  ·  anika.zaman@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

VA NY Harbor Healthcare System, New York, NYNew York, New York, United States

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