Condition: Graves' Disease · Sponsor: Immunovant Sciences GmbH
Interested? Contact the study team ↓
This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.
This description comes directly from the study's public registry record.
Central Study Contact · 18007970414 · clinicaltrials@immunovant.com
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Participants with the ability to understand the requirements of the trial, provide written informed consent, and comply with the trial protocol procedures. * Male or female participants aged ≥ 18 years. * Participants with diagnosis of GD who are hyperthyroid despite ATD treatment. * Other, more specific inclusion criteria are defined in the protocol. Exclusion Criteria: * Have previously been successfully treated with radioactive iodine (RAI) therapy or have undergone total thyroidectomy. * Have an autoimmune disease other than GD requiring treatment that, in the Investigator's judgment, puts the participant at undue risk. * Have moderate-to-severe active thyroid eye disease (TED) and are expected to require immediate surgical intervention and/or are planning corrective surgery/irradiation or medical therapy for TED during study participation. * Additional exclusion criteria are defined in the protocol.
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Site Number - 1015 | Tucson, Arizona, United States | Recruiting |
| Site Number -1014 | Concord, California, United States | Recruiting |
| Site Number - 1013 | Aurora, Colorado, United States | Recruiting |
| Site Number - 1024 | Doral, Florida, United States | Recruiting |
| Site Number - 1008 | Hialeah, Florida, United States | Recruiting |
| Site Number - 1000 | Miami, Florida, United States | Recruiting |
| Site Number - 1020 | Columbus, Georgia, United States | Recruiting |
| Site Number - 1022 | Topeka, Kansas, United States | Recruiting |
| Site Number - 1030 | Louisville, Kentucky, United States | Recruiting |
| Site Number - 1033 | Jefferson City, Missouri, United States | Recruiting |
| Site Number - 1004 | Kansas City, Missouri, United States | Recruiting |
| Site Number - 1019 | St Louis, Missouri, United States | Recruiting |
+ 146 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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