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Study identifier: NCT07018323 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Condition: Graves' Disease  ·  Sponsor: Immunovant Sciences GmbH

PhasePhase 2
Planned participants210
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where158 locations · 17 countries

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Central Study Contact  ·  18007970414  ·  clinicaltrials@immunovant.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Participants with the ability to understand the requirements of the trial, provide written informed consent, and comply with the trial protocol procedures. * Male or female participants aged ≥ 18 years. * Participants with diagnosis of GD who are hyperthyroid despite ATD treatment. * Other, more specific inclusion criteria are defined in the protocol. Exclusion Criteria: * Have previously been successfully treated with radioactive iodine (RAI) therapy or have undergone total thyroidectomy. * Have an autoimmune disease other than GD requiring treatment that, in the Investigator's judgment, puts the participant at undue risk. * Have moderate-to-severe active thyroid eye disease (TED) and are expected to require immediate surgical intervention and/or are planning corrective surgery/irradiation or medical therapy for TED during study participation. * Additional exclusion criteria are defined in the protocol.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (158)

Site Number - 1015Tucson, Arizona, United StatesRecruiting
Site Number -1014Concord, California, United StatesRecruiting
Site Number - 1013Aurora, Colorado, United StatesRecruiting
Site Number - 1024Doral, Florida, United StatesRecruiting
Site Number - 1008Hialeah, Florida, United StatesRecruiting
Site Number - 1000Miami, Florida, United StatesRecruiting
Site Number - 1020Columbus, Georgia, United StatesRecruiting
Site Number - 1022Topeka, Kansas, United StatesRecruiting
Site Number - 1030Louisville, Kentucky, United StatesRecruiting
Site Number - 1033Jefferson City, Missouri, United StatesRecruiting
Site Number - 1004Kansas City, Missouri, United StatesRecruiting
Site Number - 1019St Louis, Missouri, United StatesRecruiting

+ 146 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

TucsonConcordAuroraDoral

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