EICHORCondition: Large B-cell Lymphoma · Sponsor: The Lymphoma Academic Research Organisation
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To date, more than 300 patients have been treated with Glofitamab in the Expanded Access Programme (EAP) in France. In this study, it is proposed to perform a retrospective analysis of some of these patients. The aim is to describe the efficacy and safety of Glofitamab in the largest reported real-world cohort, with an expected median follow-up of more than 9 months. Particular focus will be given to the relapsed or refractory chimeric antigen receptors-T (CAR-T) population to confirm the response rates (CRR: 35-39%) of Glofitamab in this population and to assess the optimal timing of therapy initiation \[8, 15\].
This description comes directly from the study's public registry record.
PROJECT MANAGER · +33 4 72 66 93 33 · glorel@lysarc.org
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Inclusion Criteria: * patient enrolled in the French Glofitamab EAP for R/R DLBCL before 2024 November 1st, 2024 * patient who received at least Obinutuzumab pretreatment and one infusion of Glofitamab * adult patient * patient who is informed of the study and who did not oppose to their data collection Exclusion Criteria: * none
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| CH Victor Dupouy | Argenteuil, France | Recruiting |
| CH d'Avignon - Hôpital Henri Dufaut | Avignon, France | Recruiting |
| CH de la Côte Basque | Bayonne, France | Recruiting |
| CHRU Besançon - Hôpital Minjoz | Besançon, France | Recruiting |
| Hopital D'Instruction Des Armees Percy | Clamart, France | Recruiting |
| Hopital Henri Mondor | Créteil, France | Recruiting |
| CHU de Dijon - Hôpital le Bocage | Dijon, France | Recruiting |
| CH de Dunkerque | Dunkirk, France | Recruiting |
| CHU de Grenoble - Hôpital Albert Michallon | La Tronche, France | Recruiting |
| Hôpital de Libourne | Libourne, France | Recruiting |
| CHRU de LILLE - Claude Huriez | Lille, France | Recruiting |
| Hopital Saint Vincent-de-Paul | Lille, France | Recruiting |
+ 18 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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Source record: clinicaltrials.gov/study/NCT06994169