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Study identifier: NCT06993155 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function

Condition: Semen Quality  ·  Sponsor: ReproNovo Aps

PhasePhase 2
Planned participants200
Who can joinMale, 18 Years to 49 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The goal of this clinical trial is to evaluate three doses of the drug leflutrozole on improvement of semen quality in men. It will also study the safety of leflutrozole. The main questions it aims to answer are: * Does leflutrozole improve semen quality? * What medical problems do participants experience when taking leflutrozole? Researchers will compare leflutrozole to a placebo (a look-alike substance that contains no drug). Participants will: * Take leflutrozole or a placebo orally once a week for 16 weeks. * Visit the clinic every 4 weeks for checkups and tests. * Provide semen samples to measure changes in semen quality. * Have their blood tested to measure hormone levels and ensure safety. * Be monitored for any side effects.

This description comes directly from the study's public registry record.

Talk to the study team

Public Disclosure  ·  +45 32225466  ·  publicdisclosure@repronovo.com

Always discuss trial participation with your own doctor first.

Locations (4)

ReproNovo Investigational SiteNorth Hollywood, California, United StatesRecruiting
ReproNovo Investigational SitePomona, California, United StatesRecruiting
ReproNovo Investigational SiteGarden City, New York, United StatesRecruiting
ReproNovo Investigational SiteMiddleburg Heights, Ohio, United StatesRecruiting

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