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Study identifier: NCT06915766 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Available

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

Condition: Systemic Mastocytoses, Indolent · Systemic Mastocytoses, Aggressive  ·  Sponsor: Cogent Biosciences, Inc.

PhaseN/A
Planned participants
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this expanded access program (EAP) protocol is to provide investigational bezuclastinib to patients with a diagnosis of nonadvanced systemic mastocytosis (NonAdvSM) or advanced systemic mastocytosis (AdvSM) who have received and failed or been intolerant to at least one standard approved therapy and/or have no comparable or satisfactory alternative therapy options.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra Malinowski, PharmD  ·  1-877-633-8049  ·  EAP@cogentbio.com

Always discuss trial participation with your own doctor first.

Locations (23)

Orso Health/Modena Asthma AllergyLa Jolla, California, United StatesAvailable
Scripps Green HospitalLa Jolla, California, United StatesAvailable
UCLA Ronald Reagan Medical CenterLos Angeles, California, United StatesAvailable
Sneeze Wheeze & Itch Associates LLC Clinical Research CenterNormal, Illinois, United StatesAvailable
Indiana University HealthIndianapolis, Indiana, United StatesAvailable
Northern Light Eastern Maine Medical CenterBangor, Maine, United StatesAvailable
Walter ReedBethesda, Maryland, United StatesAvailable
AllerVie HealthGlenn Dale, Maryland, United StatesAvailable
Boston SpecialistsBoston, Massachusetts, United StatesAvailable
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesAvailable
Michigan Medicine- University of MichiganAnn Arbor, Michigan, United StatesAvailable
Mayo ClinicRochester, Minnesota, United StatesAvailable

+ 11 more locations — full list on the registry record.

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