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Study identifier: NCT06770855 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Not Yet Recruiting

Consolidative Metastasis and Primary Directed Therapy (MPDT) for Renal Cell Carcinoma (RCC)

Condition: Renal Cell Carcinoma  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhaseNA
Planned participants23
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a non-randomized, open-label phase II study designed to estimate 12-month treatment-free survival rate following total consolidative metastasis-and-primary directed therapy (MPDT) among patients with partial response/stable disease after at least 6 months of immune checkpoint blockade-based therapy for metastatic clear cell RCC. The investigators hypothesize that patients who undergo total consolidative MPDT followed by systemic therapy discontinuation will have a 12-month treatment-free survival rate of 32% compared to a null hypothesis of 13%

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Doyle  ·  610-357-6354  ·  Matthew.Doyle@Pennmedicine.upenn.edu

Naomi Haas, MD  ·  2156627615  ·  Naomi.Haas@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Abramson Cancer Center at University of PennsylvaniaPhiladelphia, Pennsylvania, United States

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