EICHORCondition: Extensive-stage Small Cell Lung Cancer (ES-SCLC) · Thoracic Neoplasms · Lung Neoplasms · Sponsor: Shanghai Pulmonary Hospital, Shanghai, China
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The study is being conducted to investigate the efficacy and safety of teniposide in patients with extensive-stage small cell lung cancer who have failed standard treatment and with high expression of the c-Myc-driven FBXW2/MYC gene. Based on the results, the study will explore the correlation between the expression of FBXW2/MYC and the efficacy of teniposide.
This description comes directly from the study's public registry record.
jiale Wang · +86 21 65115006 · wangjiale200008@163.com
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Inclusion Criteria: 1. extensive stage small cell lung cancer 2. Progression after receiving at least one chemotherapy drug treatment in the past; 3. ECOG score 0-1 4. c-Myc-driven 5. Expected survival period ≥3 months 6. Age: 18-75 years old; 7. The informed consent form complies with the ICH-GCP principles. Exclusion Criteria: 1. No measurable lesions 2. Other severe and persistent diseases or organ system dysfunction; 3. Women planning pregnancy or men planning family planning; 4. Women who are pregnant or breastfeeding; 5. Those who cannot follow the research protocol provided by the investigator.
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Shanghai Pulmonary Hospital, Shanghai, China | Shanghai, Shanghai Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06758700