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Study identifier: NCT06734234 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease

Condition: Kidney Disease  ·  Sponsor: GlaxoSmithKline

PhasePhase 1
Planned participants86
Who can joinAll sexes, 25 Years to 65 Years
Healthy volunteersYes

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This is a study where a new drug, called GSK4771261 is being tested. Neither the study doctors, study staff or participants will be aware of what treatment is being given. Part A is testing the new study treatment on healthy people. This is to see if it's safe, what it does to the body, and how the body's defense system responds to it. Part B is similar, but the study treatment will be given to people who have a kidney disease called autosomal dominant polycystic kidney disease (ADPKD).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (23)

GSK Investigational SiteRochester, Minnesota, United States
GSK Investigational SiteBrussels, Belgium
GSK Investigational SiteGhent, Belgium
GSK Investigational SiteLeuven, Belgium
GSK Investigational SiteLondon, Ontario, Canada
GSK Investigational SiteToronto, Ontario, Canada
GSK Investigational SiteMontreal, Quebec, Canada
GSK Investigational SiteBrest, France
GSK Investigational SiteParis, France
GSK Investigational SiteCologne, North Rhine-Westphalia, Germany
GSK Investigational SiteLübeck, Schleswig-Holstein, Germany
GSK Investigational SiteGroningen, Netherlands

+ 11 more locations — full list on the registry record.

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