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Study identifier: NCT06726720 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingUmbREALung

UmbREALung - A Retrospective and Prospective, Observational, Real World Multi-cohort Study of Patients With Non-small Cell Lung Cancer (NSCLC) Initiating Approved Drugs Developed by AZ or as Part of an AZ Alliance

Condition: Real World Multi-cohort Study of Patients With Non-small Cell Lung Cancer (NSCLC) Initiating Approved Drugs Developed by AZ or as Part of an AZ Alliance  ·  Sponsor: AstraZeneca

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where52 locations

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This is an ambispective, observational, multicenter and multicohort study, targeting patients with NSCLC initiating approved drugs developed by AZ or as part of an AZ alliance, in the participating countries, as monotherapy or in combination at any stage of disease. Three cohorts are designed, based on the stage of NSCLC (resectable, unresectable and metastatic). The multicohort study is modular in design. Specific modules will be set up separately to assess each new indication of drugs developed by AZ or as part of an AZ alliance once European marketing authorization (MA) has been granted and made available in the participating countries. Patients will be enrolled in the study if they have received (retrospective), receive (retrospective and prospective) or will receive (prospective) approved drugs developed by AZ or as part of an AZ alliance according to the eligibility criteria. Treatment plan and decision are made independently by each treating physician prior to inclusion in this study.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Adult patients (≥ 18 years old) * Patients with histologically or cytologically proven NSCLC * Patients initiated with approved drugs developed by AZ or as part of an AZ alliance at the time of the enrollment or within the previous three weeks. * Informed patients who consent to participate in the study as per local regulations. Exclusion Criteria: * Patients participating in an interventional clinical trial for NSCLC\* \* with the exception on low-interventional studies (RIPH2) where the intervention does not involve the NSCLC treatment * Patients already enrolled in another module of the cohort in UMBREALUNG * Patients under safeguard of justice, curatorship or guardianship

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (52)

Research SiteAix-en-Provence, FranceRecruiting
Research SiteAngers, FranceRecruiting
Research SiteAurillac, FranceRecruiting
Research SiteAuxerre, FranceRecruiting
Research SiteAvignon, FranceRecruiting
Research SiteBezannes, FranceNot Yet Recruiting
Research SiteBéziers, FranceNot Yet Recruiting
Research SiteBlois, FranceRecruiting
Research SiteBordeaux, FranceRecruiting
Research SiteBourg-en-Bresse, FranceRecruiting
Research SiteCaen, FranceNot Yet Recruiting
Research SiteCarcassonne, FranceRecruiting

+ 40 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

Aix-en-ProvenceAngersAurillacAuxerre

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