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Study identifier: NCT06713837 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.

Condition: Acute Myeloid Leukemia · Relapse/Recurrence  ·  Sponsor: Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS

PhasePhase 3
Planned participants339
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This is a multicenter, randomized, open-label, pragmatic low intervention clinical trial comparing high intensity reinduction chemotherapy with low intensity therapies in 1st or 2nd relapse Acute Myeloid Leukemia. The study is funded by European Commission (HORIZON-MISS-2022-CANCER-01-03, Project ID 101104421)

This description comes directly from the study's public registry record.

Talk to the study team

Oriana Nanni  ·  +39 0543739100  ·  cc.ubsc@irst.emr.it

Impact-aml coord Impact-aml coord  ·  impact-aml@irst.emr.it

Always discuss trial participation with your own doctor first.

Locations (47)

University Hospital BrnoBrno, CzechiaRecruiting
University Hospital Hradec KrálovéHradec Králové, CzechiaNot Yet Recruiting
University Hospital OlomoucOlomouc, CzechiaNot Yet Recruiting
University Hospital in OstravaOstrava, CzechiaNot Yet Recruiting
University Hospital in PilsenPilsen, CzechiaRecruiting
Uniklinik RWTH AachenAachen, GermanyRecruiting
University Hospital GreifswaldGreifswald, GermanyRecruiting
Krankenhaus St. Elisabeth und St. Barbara Halle (Saale) GmbHHalle, GermanyRecruiting
University Hospital HalleHalle, GermanyRecruiting
University Hospital of RostockRostock, GermanyRecruiting
Heinrich-Braun-Klinikum gGmbHZwickau, GermanyRecruiting
Policlinico Sant'OrsolaBologna, BO, ItalyRecruiting

+ 35 more locations — full list on the registry record.

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