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Study identifier: NCT06672055 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection

Condition: SARS-CoV2 · COVID-19  ·  Sponsor: Vaxart

PhasePhase 2
Planned participants5485
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of the study is to determine the relative efficacy of the investigational oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) vaccine tablet VXA-CoV2-3.3 compared to a currently recommended vaccine for the prevention of symptomatic Coronavirus Disease 2019 (COVID-19). In order to represent a more recently circulating SARS-CoV-2 variant, the main study endpoints will now evaluate the VXA-CoV2-3.3 (KP.2 strain) vaccine, and not the VXA-CoV2-3.1 (XBB.1.5 strain) vaccine.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (145)

Pinnacle Research GroupAnniston, Alabama, United States
Core Clinical Trials - Central Alabama Research LLCBirmingham, Alabama, United States
Coastal Clinical ResearchMobile, Alabama, United States
Avacare - Lenzmeier Family MedicineGlendale, Arizona, United States
Desert Clinical ResearchMesa, Arizona, United States
Velocity Clinical Research - MedPharmics - PhoenixPhoenix, Arizona, United States
Foothills Research CenterPhoenix, Arizona, United States
Avacare (CCT) - Fiel Family & Sports MedicineTempe, Arizona, United States
Baptist Health Center for Clinical Research - Little RockLittle Rock, Arkansas, United States
Elligo Health Research (BTC/ClinEdge) - Core Healthcare GroupCerritos, California, United States
Velocity Clinical Research - Chula Vista (eStudySite - Chula Vista)Chula Vista, California, United States
Avacare - Benchmark Research - SOCAL-ColtonColton, California, United States

+ 133 more locations — full list on the registry record.

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