EICHORCondition: Intensive Care Patients · Intensive Care Unit Patients · Critical Illness · Sponsor: Anders Perner
Interested? Contact the study team ↓
Among critically ill patients, many die, and many of the survivors and their family members struggle for years with reduced quality of life. Critically ill patients are treated in intensive care units (ICUs). Here, they receive life support, e.g., mechanical ventilation and advanced support of the circulation (heart and blood vessels) and kidneys. In addition, ICU patients receive many other treatments. It is, however, uncertain if all the treatments provide value for the patients. The desirable effects of many treatments are uncertain, and some may be wasteful or even harmful. Clinical trials are necessary to validly assess the desirable and undesirable effects of different treatments. However, conventional clinical trials have limitations: * They typically only assess a single question related to a single comparison of treatments at a time. * They are often not very flexible, including with regards to the number of participants needed, and this increases the risk that a trial will end up as inconclusive. * There is no or limited re-use or sharing of infrastructure across trials, leading to duplicate work and resource use. * Trial participants do usually not benefit from the obtained knowledge before the trial concludes. * Involvement of patients, family members, and other stakeholders is typically limited, which may decrease the relevance of the questions addressed. With the Intensive Care Platform Trial (INCEPT), we aim to tackle these challenges by establishing a flexi…
This description comes directly from the study's public registry record.
Anders Perner, Professor · 004535458333 · anders.perner@regionh.dk
Morten H Moeller, Professor · 004535458685 · morten.hylander.moeller@regionh.dk
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
The general eligibility criteria below apply to INCEPT as a whole and thus to all domains. Domains may impose domain-specific eligibility criteria that restrict the population eligible for that domain further, but domains are not allowed to broaden the general eligibility criteria. Domain-specific eligibility criteria always apply to all arms in a domain. PLATFORM INCLUSION CRITERIA: * Adult patient (≥18 years old) acutely admitted to the ICU. This includes ICU admissions after emergency surgery, unplanned ICU admissions after elective surgery, and prolonged ICU admissions due to complications after elective surgery (i.e., admissions occurring or being prolonged due to an unexpected, worsened condition, but excluding planned ICU admissions after elective surgery without clinical deterioration). * Eligible for at least one active domain. PLATFORM EXCLUSION CRITERIA: * Informed consent following inclusion expected to be unobtainable (e.g., known previous objections to participation). * Patient is under coercive measures (e.g., ongoing involuntary hospital stay or under the jurisdiction of correctional authorities). Patients who have previously been included in INCEPT may only be included again during new ICU admissions but may only be randomised to domains in which they have not previously been randomised. DOMAIN-SPECIFIC ELIGIBLE CRITERIA: Each domain may have additional eligibility criteria. Refer to the study website for more information (www.incept.dk).
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Anaesthesia, Hospital Sønderjylland | Aabenraa, Denmark | Not Yet Recruiting |
| Department of Anaesthesia and Intensive Care, Aalborg University Hospital | Aalborg, Denmark | Recruiting |
| Department of Intensive Care Nord , Aarhus University Hospital | Aarhus, Denmark | Recruiting |
| Department of Intensive Care Øst, Aarhus University Hospital | Aarhus, Denmark | Recruiting |
| Department of Cardiothoracic Anaesthesia and Intensive care, Copenhagen Universisty Hospital - Rigshospitalet | Copenhagen, Denmark | Not Yet Recruiting |
| Department of Intensive Care, Copenhagen University Hospital - Rigshospitalet | Copenhagen, Denmark | Recruiting |
| Neuroanaesthesiology, Copenhagen University Hospital - Rigshospitalet | Copenhagen, Denmark | Not Yet Recruiting |
| Department of anesthesiology and intensive care, Bispebjerg-Frederiksberg Hospital | Copenhagen, Denmark | Recruiting |
| Esbjerg Hospital | Esbjerg, Denmark | Not Yet Recruiting |
| Department of Anesthesiology and Intensive Care, Copenhagen University Hospital Herlev | Herlev, Denmark | Not Yet Recruiting |
| Department of Anaesthesiology and Intensive Care, Gødstrup Hospital | Herning, Denmark | Recruiting |
| Department of Anaesthesia and Intensive Care Medicine, Copenhagen University Hospital - North Zealand | Hillerød, Denmark | Recruiting |
+ 9 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06667999