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Study identifier: NCT06646471 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingPROMETHEE

PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies

Condition: Non Small Cell Lung Cancer · Lung Cancer  ·  Sponsor: GFPC Investigation

PhasePhase 4
Planned participants500
Who can joinAll sexes, 70 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where41 locations

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The objective of the study is to prospectively generate real-life data in patients aged ≥70 years treated in first line for a thoracic tumor (Non-Small-Cell Lung Carcinoma) according to best standard of care as defined by the European Society for Medical Oncology (ESMO). This cohort will aim to: * characterize participants in terms of geriatrics, biology and carcinology * describe the treatment modalities by stage, as well as the results in terms of efficacy, safety and impact on quality of life. At the same time, exploratory sub-cohorts will be identified including participants treated uniformly with the same molecule, and/or the same innovative strategy. Participants will be followed in accordance with investigator's usual clinical practice at the corresponding site. They will be asked to: * visit the clinic as per physician's request for checkups and tests for assessing general condition and clinical efficacy and tolerance of current treatment. * perform the necessary regular para-clinical examinations (lab testing, imaging, re-biopsy). * provide blood samples for bio-bank repository * perform assessments specific to older adults * answer three quality of life questionnaires

This description comes directly from the study's public registry record.

Talk to the study team

Romain CORRE, Medical Doctor  ·  +330298526404  ·  romain.corre@ch-cornouaille.fr

Soizic FERLANDIN  ·  +330663224789  ·  soizic_ferlandin@yahoo.fr

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Patient ≥70 years * Non-small-cell lung cancer for which the multidisciplinary consultation required systemic treatment regardless of Tumor-Node-Metastasis (TNM) stage * Patient naïve to systemic anticancer treatment for bronchial neoplasia * Patient covered by social security * Patient eligible for systemic treatment * Systemic treatment with marketing authorization in the indication, available in routine care early access or compassionate access. * Patient able to understand the protocol * Patient not opposed to the collection of data concerning him/her * Signature of study consent form. Exclusion Criteria: * Patients under guardians or curators * Patient not under the care of the investigating center and not monitored by the investigating center * Patient already treated with systemic therapy for NSCLC

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (41)

CH du Pays d AixAix-en-Provence, FranceRecruiting
Hôpital Henri DuffautAvignon, FranceRecruiting
Institut du Cancer d'AvignonAvignon, FranceRecruiting
CH BastiaBastia, FranceNot Yet Recruiting
Oncologie Thoracique Hôpital MorvanBrest, FranceRecruiting
Pneumologie Centre François BaclesseCaen, FranceNot Yet Recruiting
CH Métropole-SavoieChambéry, FranceRecruiting
Centre Hospitalier du CotentinCherbourg, FranceRecruiting
CHU Hôpital MontpiedClermont-Ferrand, FranceNot Yet Recruiting
Pneumologie Hospices Civils de ColmarColmar, FranceRecruiting
Pneumologie CHI CreteilCréteil, FranceRecruiting
CH ElbeufElbeuf, FranceRecruiting

+ 29 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

Aix-en-ProvenceAvignonBrestChambéry

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