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Study identifier: NCT06611813 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Neoadjuvant Chemotherapy in Combination With Toripalimab for HR+/HER2- Breast Cancer (NEOTORCH-BREAST01)

Condition: HR+/HER2- Breast Cancer  ·  Sponsor: First Affiliated Hospital of Zhejiang University

PhasePhase 2
Planned participants30
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study is a prospective, single arm, multi-center phase II clinical trial. The primary study objective is to evaluate the pathologic complete response(PCR)and RCB0-1 ratio of neodjuvant treatment of HR+/HER2- breast cancer with Toripalimab combined with neoadjuvant chemotherapy and sequential Toripalimab monoclonal antibody, including the incidences and types of adverse events. The secondary study objective is to observe and evaluate the disease-free survival (DFS), Progression-Free-Survival (PFS ),and Objective Response Rate(ORR)

This description comes directly from the study's public registry record.

Talk to the study team

Zhijun Dai  ·  +86 157 0581 9132  ·  dzj0911@126.com

Youyi Chen  ·  +86 157 5751 5017

Always discuss trial participation with your own doctor first.

Locations (11)

The First Affiliated Hospital of Zhejiang UniversityHangzhou, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, ChinaRecruiting
Harbin Medical University Cancer HospitalHarbin, ChinaNot Yet Recruiting
The First Affiliated Hospital of Anhui Medical UniversityHefei, ChinaNot Yet Recruiting
Jinhua Municipal Central HospitalJinhua, ChinaNot Yet Recruiting
Nanchang People's HospitalNanchang, ChinaNot Yet Recruiting
Zhongshan Hospital, Fudan UniversityShanghai, ChinaNot Yet Recruiting
Xinjiang Medical University Affiliated Cancer HospitalÜrümqi, ChinaNot Yet Recruiting
Shaanxi Provincial Cancer HospitalXi'an, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an, ChinaRecruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, ChinaNot Yet Recruiting

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