Condition: Gastrointestinal Neoplasm · Sponsor: Karen-Lise Garm Spindler
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A study investigating if analysis of circulating tumor DNA (ctDNA) can guide palliative treatment in patients with gastrointestinal cancer.
This description comes directly from the study's public registry record.
Karen-Lise G Spindler, MD, Prof · +4591167244 · k.g.spindler@rm.dk
Torben F Hansen, MD, Prof · torben.hansen@rsyd.dk
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Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Incurable metastatic gastrointestinal cancer * Indication for first or second-line systemic treatment * Measurable disease according to RECIST v.1.1 * CT of chest and abdomen less than 30 days old at time of treatment initiation * Age at least 18 years * ECOG performance status 0-2 * Clinically eligible systemic palliative treatment at investigators decision. * Adequate bone marrow, liver and renal function allowing systemic chemotherapy * Anticonception for fertile women and for male patients with a fertile partner. Intrauterine device, vasectomy of a female subject's male partner or hormonal contraceptive are acceptable * Written and verbally informed consent Exclusion Criteria: * Incapacity, frailty, disability and comorbidity to a degree that according to the investigator is not compatible with combination chemotherapy * Other concurrent malignant tumor except non-melanoma skin cancer or carcinoma in situ cervicis uteri * Pregnant (positive pregnancy test) or breast-feeding women
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Aarhus University Hospital | Aarhus, Denmark | Recruiting |
| Department pf Oncology, Vejle Hospital | Vejle, Denmark | Recruiting |
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