EICHORCondition: Chronic Kidney Disease · Sponsor: Bayer
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), CKD is a condition in which the kidneys' ability to work properly gradually decreases over time. A common sign of decreasing kidney function is the body losing too much of a protein called albumin in the urine. This condition is known as albuminuria. This can lead to a faster decline in kidney function. People who have high blood pressure and diabetes are more likely to have CKD and are at a higher risk of complications related to it. BAY3283142 is a new drug that is being developed to treat people with CKD. It works by activating a protein that helps relax blood vessels and is thought to have beneficial effects in CKD. In this study, researchers want to learn about how well different doses of BAY3283142 work when taken with standard treatment for CKD in reducing albumin in the urine of participants with CKD. They will compare the results of the change in the urine albumin-creatinine ratio (UACR) after 16 weeks for BAY3283142 with a placebo. A placebo looks like the study drug but does not have any medicine in it. During the study, participants will take either of the following drugs: * BAY3283142: Participants will take BAY3283142 as tablets by mouth. * Placebo: Participants will take it in the same way as BAY3283142. Participants will continue taking the available standard treatment for CKD and other conditions they may have (for example, heart conditions and diabetes). At t…
This description comes directly from the study's public registry record.
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| Nephrology Consultants, LLC | Huntsville, Alabama, United States | — |
| Balboa Research SMO+ - Chula Vista | Chula Vista, California, United States | — |
| California Kidney Specialists - San Dimas | San Dimas, California, United States | — |
| Yale Nephrology Clinical Research Clinic | New Haven, Connecticut, United States | — |
| Nova Clinical Research - Blake Medical Center | Bradenton, Florida, United States | — |
| Renstar Medical Research - Deerwood Clinic | Ocala, Florida, United States | — |
| Elixia Central Florida | Orlando, Florida, United States | — |
| Florida Institue for Clinical Research | Orlando, Florida, United States | — |
| Southeastern Clinical Research Institute, LLC | Augusta, Georgia, United States | — |
| Research by Design, LLC | Chicago, IL | Chicago, Illinois, United States | — |
| Nephrology Associates of Northern Illinois and Indiana - Hinsdale | Hinsdale, Illinois, United States | — |
| Triad Internal Medicine - Asheboro | Asheboro, North Carolina, United States | — |
+ 141 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06522997