Condition: Advanced Colorectal Carcinoma · Immunotherapy · Sponsor: Fudan University
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Study Title: A Prospective, Randomized, Phase II, Multicenter Clinical Study of Serplulimab Combined with Targeted Therapy, Chemotherapy, and Optional Radiotherapy in Advanced Colorectal Cancer Study Objective: To explore the efficacy and safety of immune checkpoint inhibitor combined with targeted therapy and chemoradiotherapy in locally advanced unresectable or metastatic colorectal cancer. Study Population: Patients with left-sided wild-type, right-sided, or RAS-mutant advanced colorectal cancer who have not received systemic treatment. Study Endpoints: Progression-free survival (PFS), objective response rate (ORR), overall survival (OS), safety, and R0 resection rate. Study Design: Prospective, randomized Phase II clinical study.
This description comes directly from the study's public registry record.
Dawei Li, PhD · 13774201693 · li_dawei@fudan.edu.cn
Always discuss trial participation with your own doctor first.
| Fujian Cancer Hospital | Fuzhou, Fujian, China | Not Yet Recruiting |
| The First Affiliated Hospital of Xiamen University | Xiamen, Fujian, China | Not Yet Recruiting |
| Lanzhou Military Region General Hospital | Lanzhou, Gansu, China | Not Yet Recruiting |
| The First Affiliated Hospital of Zhengzhou University | Zhengzhou, Henan, China | Not Yet Recruiting |
| Huai'an Second People's Hospital | Huaian, Jiangsu, China | Not Yet Recruiting |
| Qianfoshan Hospital of Shandong Province | Jinan, Shandong, China | Not Yet Recruiting |
| Taian City Central Hospital | Taian, Shandong, China | Not Yet Recruiting |
| Fudan University Shanghai Cancer Center | Shanghai, Shanghai Municipality, China | Recruiting |
| Yunnan Cancer Hospital | Kunming, Yunnan, China | Not Yet Recruiting |
| Anyang Cancer Hospital | Anyang, China | Not Yet Recruiting |
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