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Study identifier: NCT06507306 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Condition: Solid Tumor, Adult  ·  Sponsor: Kumquat Biosciences Inc.

PhasePhase 1
Planned participants92
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if KQB198 works to treat advanced solid tumor cancer in adults. It will also learn about the safety of KQB198. The main questions it aims to answer are: * What is the safe dose of KQB198 by itself or in combination with other anti-cancer drugs? * Does KQB198 alone or in combination with other anti-cancer drugs decrease the size of the tumor? * What happens to KQB198 in the body? Participants will: * Take KQB198 daily, alone or in combination with another anti-cancer drug * Visit the clinic about 8 times in the first 8 weeks, and then once every 4 weeks after that

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (26)

Sarah Cannon Research Institute at HealthONEDenver, Colorado, United States
Sarah Cannon Research Institute at Florida Cancer Specialists - Lake Nona -Orlando, Florida, United States
Florida Cancer Specialists - SarasotaSarasota, Florida, United States
Henry Ford Health SystemDetroit, Michigan, United States
David H. Koch Center for Cancer Center at Memorial Sloan Kettering Cancer CenterLong Island City, New York, United States
The Lindner Center for Research and Education at The Christ HospitalCincinnati, Ohio, United States
Sarah Cannon and HCA Research InstituteNashville, Tennessee, United States
New Experimental Therapeutics of San Antonio - NEXT OncologySan Antonio, Texas, United States
New Experimental Therapeutics of Virginia - NEXT OncologyFairfax, Virginia, United States
Institut Paoli-CalmettesMarseille, Bouches-du-Rhône, France
Institut de Cancerologie de l'Ouest - site St-HerblainSaint-Herblain, Loire-Atlantique, France
CHU Bordeaux - Hopital Saint-AndreBordeaux, Nouvelle-Aquitane, France

+ 14 more locations — full list on the registry record.

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