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Study identifier: NCT06496607 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not RecruitingRAINIER

A Study to Evaluate Solriktug in Adult Participants With Asthma

Condition: Asthma  ·  Sponsor: Uniquity One (UNI)

PhasePhase 2
Planned participants145
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where69 locations

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Key inclusion criteria: * Participant must be aged 18 to 75 years of age. * Documented diagnosis of asthma at least 12 months prior to Screening. * Participants must be on maintenance asthma medications, for at least 3 months prior to screening: inhaled corticosteroid (ICS) in combination with long-acting beta agonist (LABA), or as part of an approved triple therapy for asthma (ICS/LABA/long-acting muscarinic antagonist \[LAMA\]). * Participant has an ACQ-6 score ≥1.5 at Screening Visit. * Participant has FEV1 of ≥50% to 90%, inclusive, of predicted normal value at Screening Visit 1. * Evidence of asthma as documented by reversibility in FEV1 of ≥12% and ≥200 mL over the pre-salbutamol FEV1 at Screening Visit. Key exclusion criteria: * Female participant who is pregnant or breastfeeding. * Participant is a current smoker, or former smoker with a smoking history of ≥10 pack-years. * Participant has a known hypersensitivity to any component of the formulation of solrikitug, including any of the excipients, or a history of anaphylactic reaction to any therapeutic monoclonal antibody. * Participant has history or evidence of any clinically significant cardiovascular, hematologic, hepatic, immunologic, metabolic, urologic, neurologic, dermatologic, psychiatric, renal and/or other major disease or malignancy, or any other condition (risks factors of pneumonia) that in the opinion of the Investigator might obfuscate the study data. * Participant has an exacerbation of asthma requiring use of OCS or hospitalization in the 6 weeks prior to Screening or during the Screening Period. * Participant has history or evidence of any clinically significant pulmonary condition, other than asthma. * Lower respiratory tract infection within the 6 weeks prior to Screening.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (69)

Velocity Clinical ResearchMobile, Alabama, United States
Phoenix Medical GroupPeoria, Arizona, United States
Warren W. Pleskow, M.D.Encinitas, California, United States
Beach Physicians Clinical Research Corp.Huntington Beach, California, United States
Biosolutions Clinical Research CenterLa Mesa, California, United States
Orso HealthLong Beach, California, United States
Downtown LA Research CenterLos Angeles, California, United States
Newport Native MD, Inc.Newport Beach, California, United States
Prospective Research Innovations Inc.Rancho Cucamonga, California, United States
Allergy & Asthma Medical Group and Research CenterSan Diego, California, United States
Allergy & Asthma Associates of Santa Clara ValleySan Jose, California, United States
San Jose Clinical TrialsSan Jose, California, United States

+ 57 more locations — full list on the registry record.

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