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Study identifier: NCT06451445 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: University Health Network, Toronto

PhaseNA
Planned participants100
Who can joinMale, 50 Years to no upper limit
Healthy volunteersNo

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About this study

The goal of this clinical trial is to investigate the safety and efficacy of Irreversible Electroporation (IRE) using NanoKnife technology in patients with intermediate-risk prostate cancer. This patient population was chosen because they would otherwise be treated with conventional therapies with high side effects. The main questions it aims to answer are: 1. Is the NanoKnife system is effective at damaging prostate tumour cells, and killing the cancer? 2. Are there any safety concerns with the procedure, or major side effects caused by the treatment? Participants will undergo IRE treatment with the NanoKnife system, and then complete follow-up appointments for 12-months after the procedure.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

Princess Margaret Cancer CentreToronto, Ontario, CanadaRecruiting

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