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Study identifier: NCT06413953 Synced from ClinicalTrials.gov · August 10, 2026
● Study status: Recruiting

A Clinical Study of TQB3107 Tablets in Patients With Malignant Tumors

Condition: Advanced Cancers  ·  Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

PhasePhase 1
Planned participants140
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where12 locations

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

TQB3107 is an target inhibitor that binds to target to induce apoptosis and inhibits the proliferation of a variety of tumor cells. This is a clinical study to evaluate the safety and tolerability of TQB3107 tablets in subjects with advanced malignancies, to determine dose-limiting toxicities (DLTs), maximum tolerated dose (MTD) (if any), and the recommended dose for Phase II (RP2D).

This description comes directly from the study's public registry record.

Talk to the study team

ZhiMing Li, Doctor  ·  13719189172  ·  lzmsysu@163.com

HuiLai Zhang, Doctor  ·  18622221228  ·  zhlwgq@126.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * 18 years ≤ age≤ 75 years (calculated from the date of signing the informed consent); Score 0\~1 point, estimated survival ≥ 3 months; * Advanced malignant tumor; * The major organs are functioning well; * Negative serum pregnancy test within 7 days prior to the first dose and must be a non-lactating subject, female and male subjects of childbearing potential should agree to use contraception throughout the study and for 6 months after the study ends; * Subjects voluntarily participated in this study, signing the informed consent form and demonstrating good compliance. Exclusion Criteria: * Hematologic malignancy has or is suspected to involve the central nervous system, or primary central nervous system lymphoma; * Received any anti-cancer therapy such as major surgery, chemotherapy and/or radiotherapy, immunotherapy, or targeted therapy within 4 weeks prior to the first dose; * Combined with severe or not well-controlled diseases, which the investigator judges to be at greater risk of entering this study; * Those with a history of drug addiction or substance abuse; * According to the judgment of the investigator, there are concomitant diseases that seriously endanger the safety of the subjects or affect the completion of the study, or subjects who are considered to be unsuitable for enrollment for other reasons.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (12)

Sun Yat-sen University Cancer CenGuangzhou, Guangdong, ChinaRecruiting
The Fifth Affiliated Hospital Sun Yat-sen UniversityZhuhai, Guangdong, ChinaRecruiting
The Affiliated Hospital of Chengde Medical CollegeChengde, Hebei, ChinaRecruiting
Harbin Medical University Cancer HospitalHarbin, Heilongjiang, ChinaRecruiting
Hunan Cancer HospitalChangsha, Hunan, ChinaRecruiting
The First People's Hospital Of ChangzhouChangzhou, Jiangsu, ChinaRecruiting
Shandong Medical And Pharmaceutical University HospitalBinzhou, Shandong, ChinaRecruiting
Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting
West China Hospital,Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
The Affiliated Hospital of Southwest Medical UniversityLuzhou, Sichuan, ChinaRecruiting
Tianjin Municipality LocationsTianjin, Tianjin Municipality, ChinaRecruiting
The First Affiliated Hospital, Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaWithdrawn

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

GuangzhouZhuhaiChengdeHarbin

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