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Study identifier: NCT06396065 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

Phase III Study of AK112 for NSCLC Patients

Condition: Non-Squamous Non-small Cell Lung Cancer  ·  Sponsor: Summit Therapeutics

PhasePhase 3
Planned participants420
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A Randomized, Double-blind, Multi-center, Phase III Clinical Study of AK112 or Placebo Combined With Pemetrexed and Carboplatin in Patients With EGFR-mutant Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Who Have Progressed on or Following Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI) Treatment (HARMONi)

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (74)

CBCC Global ResearchBakersfield, California, United States
UC San DiegoLa Jolla, California, United States
University of Southern CaliforniaLos Angeles, California, United States
Valkyrie Clinical TrialsLos Angeles, California, United States
UCLA Department of Medicine - Hematology/OncologyLos Angeles, California, United States
Palo Alto Medical Foundation Research InstituteMountain View, California, United States
Providence St. JosephOrange, California, United States
UC IrvineOrange, California, United States
Sutter Cancer centerSacramento, California, United States
UC DAVIS Comprehensive Cancer CenterSacramento, California, United States
Sharp Memorial HospitalSan Diego, California, United States
California Pacific Medical CenterSan Francisco, California, United States

+ 62 more locations — full list on the registry record.

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